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Topical Antifungals (Types of Topical (butoconazole, clotrimazole,…
Topical Antifungals
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contraindications
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Econazole can cause intense, local burning, and irritation.
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Naftifine, oxiconazole, and sertaconazole have risk of adverse effects and possible emergency of resistant fungal strains.
Side Effects
Local: irritation, burning, rash, swelling
GI: nausea, vomiting, hepatic dysfunction
GU: urinary frequency, burning, change in sexual activity
Mechanism of Action
Altering the cell permeability of the fungus, causing prevention of replication and fungal death.
Indications
Local treatment for mycoses, including tinea infections.
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