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Pneumocystis Jiroveci (Investigative Procedure (Blood test, Sputum…
Pneumocystis Jiroveci
Investigative Procedure
Blood test
Sputum collection
Polymerase chain reaction
Chest X-ray
Biopsy
Broncho-alveolar lavage
Endoscopic aspirates
Causes
.
Cancer
Long-term use of corticosteroids or other medicines that weaken the immune system
HIV/AIDS
Organ or bone marrow transplant
Definition
Lung infection caused Pneumocystis jirovecii
.
Clinical Manifestations
.
Fever
Cough
Progressive Dyspnea
Oxygenation desaturation
Treatment
.
Corticosteroids are given patients with HIV
Prevention of smoking cessation and chemoprophylaxis
Antibiotics are the primary treatment
Pathiophysiology
,
Uncontrolled replication of Pneumocystis organisms
Alveolar macrophages unable to eradicate organisms.
Once inhaled, organism attaches to alveoli.
Increased alveolar-capillary permeability is visible
Occurs when both immunity is defective.
Signs and Symptoms
Hypoxemia
Respiratory alkalosis
Impaired diffusing capacity
Changes in total lung capacity