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Chance, Bias & Confounding (Controlling SB (encouraging participation…
Chance, Bias & Confounding
Systematic Error
- It's NOT caused by chance
When there is a systematic difference between the characteristics of the sample and source population.
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When there is a systematic difference between those in the source population and thepeople that actually are enrolled/stay enrolled in a study
Examples:
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- Inaccuracies in Objective
When there is a systematic inaccuracy in the measurement or classification of the disease or exposure
Controlling SB
- encouraging participation rates
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- measures to ensure the sample is representative of the source population
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Controlling IB
- standardizing data collection tools
- blinding the interviewer to the subject’s status
- clear and concise wording for questionnaires
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