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Budd-Chiari syndrome (Risk factors (Pregnancy, OCP/HRT, MDS/malignancy,…
Budd-Chiari syndrome
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Management
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Conservative
Infromation, advice, support
Identify and treat cause
Refer to gastro/general surg asap
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Diagnosis
Examination
Abdo exam
Acute: jaundice, tender liver,
hepatomegaly, ascites
Investigations
Bloods
FBC, CRP, U+E, LFT (deranged),
clotting (may be deranged)
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History
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FH
DVT/stroke, coag disorder
PMH
Malignancy, pregnancy,
coagulopathy
SH
Living arrangements, occupation,
smoking, alcohol, drugs
PC/HPC
Jaundice, abdo pain,
distension, generally unwell
Pathophysiology
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Mechanism
Congestive liver ischemia
Inflammation, necrosis of hepatocytes
Can lead to acute or chronic liver failure
(usually chronic)
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Definition
Obstruction of the hepatic
vein, causing liver damage
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