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Ageing and Cell Death (Somatic mutation and genomic instability (Under…
Ageing and Cell Death
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Why apoptosis?
Development: Immune systems maturation, mophogenesis, neural development
Adult: immune privelege, DNA damage and wound repair
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Programmed cell death: Apoptosis - Characterized by shrinkage of the cell body. Blebbing of the cell membrane, chromatin condensation, fragmentation of the nucleus, cleavage of chromosomal DNA and divison into numerous cell fragments.
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Necrosis Killing, decay and destruction