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Translation (3 stages: (Initiation: Ribosomal complex and 1st tRNA binds,…
Translation
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Ribosome
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Both subunits are composed of long strands of RNA, dotted with protein chains
Initiaition
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Downstream of this on the mRNA is the start codon AUG, The anticodon of the complementary tRNA charged with methione binds to the mRNA
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Elongation
The process by which appropriate amino acid tRNAs are sequentially brought into the correct position.
Linked together by a peptide bond using one of the inherent proteins of the larger ribosomal subunit - peptidyl transferase.
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Small ribosomal subunit initially binds to mRNA like a latch. and also binds tRNA's at the A and the P sites
It controls information flow, whilst the large subunit controls the chemistry - Both help form the groove in which mRNA binds.
Peptidyl transferase
resides in the large ribosomal subunit and catalyses two principle chemical reactions of protein synthesis
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Codon: is a seuence of three RNA nucleotides that corresponds with a specific amino acid or stop signal during protein synthesis
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Termination of translation starts at a termination codon UAA,UAG or UGA - when a termination codon enters the A site of the ribosome, termination is initiated