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GIGANTISM (signs and symtoms (excessive sweating, severe or recurrent…
GIGANTISM
PATHOPHYSIOLOGY
Gigantism is a rare condition that causes abnormal growth in children. This change is most notable in terms of height, but girth is affected as well. It occurs when your child’s pituitary gland makes too much growth hormone, which is also known as somatotropin.
CAUSES
McCune-Albright syndrome causes abnormal growth in bone tissue, patches of light-brown skin, and gland abnormalities.
Carney complex is an inherited condition that causes noncancerous tumors on connective tissue, cancerous or noncancerous endocrine tumors, and spots of darker skin.
Multiple endocrine neoplasia type 1 (MEN1) is an inherited disorder that causes tumors in the pituitary gland, pancreas, or parathyroid glands.
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DIAGNOSTIC STUDIES
Blood test will be done to measure the levels of insulin like growth factor(IGF-I), (GHRH), And other pituiutary hormones
a glucose tolerance test may also be done to see if the GH level drops- it will not drop in case of acromegally
IF ACROMEECAGALLY IS CONFIRMED THE FOLLOWING TESTS MAY BE DONE TO LOCATE THE TUMOR THAT IS CAUSING DISORDER
Head CT scan- a type of X-ray that uses a computer make pictures of the ibside of the brain and sororunding structures
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