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The function of the liver (CARBOHYDRATE METABOLISM (When blood glucose is…
The function of the liver
CARBOHYDRATE METABOLISM
closely involved in
homeostatic control
of
glucose
When blood glucose is
HIGH
,
insulin
levels
RISE
stimulating
Hepatocytes
Converting
Excess Glucose
to
Glycogen
When blood sugar levels are
LOW
Hepatocytes convert
GLYCOGEN
to
GLUCOSE
under influence of hormone
GLUCAGON
DEAMINATION
OF
EXCESS AMINO ACIDS
REMOVAL
of an
Amine Group
Removing the amino group
1st converted into
AMMONIA
Then converted to
UREA
EXCRETED
by the
Kidney
DETOXIFICATION
Hepatocytes contain
Catalase
splits
hydrogen peroxide into
Oxygen
and
Water
An enzyme
Ethan
ol
Breaks down to
Ethan
al
ORNITHINE CYCLE
UREA
is less
toxic
and
more manageable
AMMONIA
is converted into
UREA
in a set of
enzyme-controlled
reactions
VERY TOXIC
TOXIC
IN
HIGH CONCENTRATIONS
Toxic substances made Harmless
ALCOHOL DEHYDROGENASE