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DIABETIC COMPLICATION (Microvascular (symptoms (squeezing or discomfort…
DIABETIC COMPLICATION
Macrovascular
pathophysiology
The central pathological mechanism in macrovascular disease is the process of atherosclerosis, which leads to narrowing of arterial walls throughout the body. Atherosclerosis is thought to result from chronic inflammation and injury to the arterial wall in the peripheral or coronary vascular system.
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Microvascular
Pathophysiology
microvascular complication result from changes that are unique to diabetes in small blood vessel and occur in both type1 and type2 diabetes. the basement of the capillaries thickens due to the accumulation of sugars which impair exchange of nutrients, gases and waste
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risk factors
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ncreasing age, older than 45 in men and older than 55 in women