-Insidious and slow onset ,loss of appetite while gaining weight due to slow metabolism rate.
-Sluggishing in both physical and mental activities.
-Cold intolerance ,disturbed memory ,fatigue and sleeping for long hours.
-Constipation ,flactulence ,and abdominal distension.
-Husky voice ,depression ,coarse skin and brittle hair and nails.
-Swollen face with eyelids.
-Enlarged thyroid gland.