Please enable JavaScript.
Coggle requires JavaScript to display documents.
THYROID STORM (Clinical features (CV (possible a-fib +/- rvr, HF:…
THYROID STORM
Clinical features
Vitals
-
-
hyperpyrexia, 104-106 deg F
-
Neuropsych
agitation, anxiety, delirium, psychosis, stupor, or coma
Eyes
ophthalmopathy (in s/o Grave's), lid lag
Extremities
hand tremor, warm / moist skin
Abdomen
severe nausea, vomiting, diarrhea, abdominal pain, or hepatic failure with jaundice
-
Treatment
-
-
-
-
Glucocorticoids to reduce T4-to-T3 conversion, promote vasomotor stability, possibly reduce the autoimmune process in Graves' disease, and possibly treat an associated relative adrenal insufficiency
-
-
Labs
-
other, nonspecific findings
mild hyperglycemia (secondary to a catecholamine-induced inhibition of insulin release and increased glycogenolysis)
mild hypercalcemia (hemoconcentration, enhanced bone resorption)
-
-
Epidemiology
studies from US & Japan, respectively
hospitalized pts
4.8 to 5.6 per 100,000 persons per year
non-hospitalized pts
0.57 to 0.76 and 0.20 per 100,000 persons per year
-
Diagnostic criteria
-
Burch HB, Wartofsky L. Life-threatening thyrotoxicosis. Thyroid storm. Endocrinol Metab Clin North Am 1993; 22:263.
-