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Rhabdomyosarcoma (Diagnosis (Investigations (Bedside
Obs (nil)
…
Rhabdomyosarcoma
Diagnosis
Examination
ENT
Nasal obstruction, nasal discharge
Abdominal
Abdominal mass, distended bladder
-
Investigations
-
-
Bloods
FBC (anaemia), CRP, U+E (dysfunction if GU), LFTs
-
-
History
Head and neck symptoms, genitoruinary symptoms,
often vague (can arise anywhere), weight loss, fatigue
Management
Medical
Chemotherapy
Indication: alongside RT, surgery (multimodality)
Radiotherapy
Indication: alongside chemo, surgery (multimodality)
Surgical
Excision
Indication: alongside RT, chemo (multimodality)
Conservative
Information, advice, support
MDT (medic, surgeon, specialist nurse,
psychologist, counselling)
Pathophysiology
-
Can arise from many sites, usually head
and neck, also genitourinary
Metastatic disease to lung, liver, bone
Clinical
presentation
Genitourinary
Dysuria, urinary retention
Bloody vaginal discharge
Scrotal mass
Head and neck
Nasal obstruction, bloody discharge
Proptosis
-
-
-