Please enable JavaScript.
Coggle requires JavaScript to display documents.
Darren Butarbutar - Lymphatic/Immune System (Anatomy of the lymphatic…
Darren Butarbutar - Lymphatic/Immune System
Innate/Natural vs Adaptive/Acquired
Immune Defenses
Innate/Natural Defense
Innate immunity is an immunological subsystem that comprises the cells and mechanisms that provide the first line of defence from infection in a non-specific manner. Innate immune responses are rapid and independent of antigen.
Adaptive/Acquired Defense
a subsystem of the overall immune system that is composed of highly specialized, systemic cells and processes that eliminate pathogens or prevent their growth.
Major Functions: Lymphatic & Immune System
Immune System
A systematic order of cells that work together to protect the body. There are different lines of defense; each line has different functions and types of cells.
Lymphatic System
The lymphatic system is a network of tissues and organs that help rid the body of toxins, waste and other unwanted materials. The primary function of the lymphatic system is to transport lymph, a fluid containing infection-fighting white blood cells, throughout the body
Anatomy of the lymphatic System
(vessels, nodes, MALT, spleen and thymus)
MALT
a form of lymphoma involving the mucosa-associated lymphoid tissue (MALT), frequently of the stomach, but virtually any mucosal site can be afflicted.
Spleen
clearing worn-out red blood cells and other foreign bodies from the bloodstream to help fight off infection.
Vessels
Subcapsular sinus
Medullary Sinus
Afferent lymphatic vessels
Hilum
efferent lymphatic vessels
Thymus
this gland's primary function is to promote the development of cells of the immune system called T lymphocytes.
Tonsils
Helps fight infections (Located near the thorax)
Peyer's Patches
large clusters of lymphoid follicles, structurally similar to tonsils
Appendix
(1) prevent bacteria, (2) generate memory lymphocytes
Humoral vs Cellular Response
Cellular Response
Cell surface receptors work in several ways when they are occupied. Some receptors enter the cell still bound to the chemical signal. Others activate membrane enzymes, which produce certain intracellular chemical mediators.
Humoral Response
The immune response involving the transformation of B cells into plasma cells that produce and secrete antibodies to a specific antigen.
Antigens and Antibodies
Antibody
a blood protein produced in response to and counteracting a specific antigen. Antibodies combine chemically with substances which the body recognizes as alien, such as bacteria, viruses, and foreign substances in the blood.
Antigen
a toxin or other foreign substance which induces an immune response in the body, especially the production of antibodies.
Disorders of the Immune System
Septic Shock
A dangerous condition in which the imflammatory response goes out of control. It results from especially severe bacterial infections or more ordinary infections that grow rapidly worse in patients with weakened defenses
Systemic lupus erythematosus (SLE)
A systemic autoimmune disorder that occurs mainly in young females. Diagnosis is helped by finding antinuclear antibodies in the patient's blood
Eczema
These features of immediate hypersensivity, and usually begins in the first five years of life. This is a clinical term for several conditions that cause "weepings" skin lesions and intense inching