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CR - Myocarditis (signs + symptoms (mild fever, ECG changes, arrhythmias…
CR - Myocarditis
signs + symptoms
mild fever
ECG changes
arrhythmias common
congestive heart failure
sudden death
v variable depending on cause
causes (think i's of inflamm)
infection
CMV
coxsackie
neisseria
candida
toxoplasmosis
GAS (rheumatic fever)
if parasitic organism may be seen (e.g. American trypanosomiasis in Chagas disease)
immune-mediated
post virus/GAS
SLE
drug hypersensitivity (chemo)
transplant rejection
idiopathic
sarcoidosis
giant cell myocarditis
acute viral myocarditis
myocardial oedema
mononuclear + lymphocytic infiltrate
non-ischaemic necrosis
rarely viral inclusions-sites of viral rep (e.g. CMV)
inflamm of myocardium
pimary injury to myocytes
inflamm alone is not a Dx as could be cseondary to something else (e.g. ischaemia)
results in resolution or chronic fibrosis
progression
ventricular dilation
myocardial fibrosis
abscesses if bacterial