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Lymphatic and Immune System, Julie Abundis (lymphatic system anatomy…
Lymphatic and Immune System, Julie Abundis
major functions
defense system
removal of interstitial fluid
transports fatty acids
transport wbc from lymph nodes to bones
returns fluid back
lymphatic system anatomy
lymph nodes
attack is planned
macrophages or general immune response
organs
spleen
productions of lymphocytes
thymus
productions of lymphocytes
tonsils
adenoids
lymphatic vessels
work under lower pressure
series of valves that prevent back flow
lymph trunk
lymphatic capillaries
get blood from capillaries
made of endothelial cells with flap like valves
lymph duct
feed back into circulatory system
MALTs
mucosa-associated lymphoid tissues
tonsils
peyers patches
small intestine
simple line of defense
skin barrier
keratinized epithelial membrane
mucous membrane barrier
adaptive defense
antigen specific immune response
more complex
created in response to exposure
memory to fight off virus in invades body again
humoral
b cells turn into plasma cells
freely circulating
antibody mediated immunity
antigens
triggers formation of antibodies
Exogenous
Endogenous
Autoantigens
interacts with antibodies in epitopes
can cause disease or allegric reaction
innate defense
fever
inflammation
chemical signals
phagocytes
neutrophils
most abundant in wbc
die after engulfing pathogen
macrophages
free types
fixed types
uses cytoplasmic extensions
natural killer cells
portal blood and lymph
kills own cells if infected
cellular
occurs in infected cells
pathogen expressed on cell surface
t cells bind to infected MHC antigen
antibodies
proteins
5 basic antibodies
protect body by immobilization
paratope