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The lymphatic System (The Functions (Recycling fluids lost form…
The lymphatic System
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Types of leukemia
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Acute leukemia: have rapid onset of symptoms; overproduced WBCs are immature, non-functional cells
Chronic leukemia: have gradual onset overproduced WBCs are mature, functional cells
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Lymphocyte Proliferation
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The activated lymphocytes must make thousands of copies of themselves in order to fight off the thousands of pathogens reproducing in the body.
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job of the helper T cells help other lymphocytes; must be many of these cells before other lymphocytes activated
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Fever
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The effect of cytokine is to elevate the temperature set-point, or produce a fever
Rise in body temperature is a deliberate attempt by immune system to destroy pathogens by ‘baking’ them out
Rheumatoid arthritis
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Leads to destruction of bone and cartilage in joints, weakening of soft tissue supporting joints
can result in: joint collapse, fusion of bones, shortening of tendons, disfigurement (particularly of hands and feet)
Lymphocyte Activation
Lymphocytes develop, mature, and are selected when you are young; they begin as undifferentiated cells, with potential to become anything
During maturation process they become differentiated, growing to be specialized cells with special function
Undifferentiated lymphocytes produced in bone marrow and some migrate to thymus, destined to become T cells
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Regulatory T cells
Are “off switch” for immune system, turn off response when threat over
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Suggested they directly inhibit B cells and cytotoxic T cells, releasing cytokines that decrease immune and inflammatory response
Inflammation
Typical symptoms: pain, swelling, heat, and redness
Deliberate action of body in response to tissue damage,
HIV and AIDS
Acquired Immune Deficiency Syndrome (AIDS): immune deficiency disorder caused by infection with Human Immunodeficiency Virus (HIV)
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Primary response
antibodies bind to antigens of infecting cells, destroying pathogen by
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Memory T cells
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Like memory B cells, responsible for secondary response, adaptive immunity’s ability to improve with experience
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