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Wound healing by Secondary Intention (Day 1 (Bleeding, coagulum forms…
Wound healing by
Secondary Intention
Day 1
Bleeding, coagulum forms
Dehydration of coagulum,
eschar (scab) formation
Acute inflammation at wound
margins (exudate/infiltrate
)
Day 2-3
Vascular granulation tissue forms replacing the acute
inflammatory exudate/infiltrate (Organization)
Fibroblasts
Vascular sprouts
Macrophages
Re-epithelialisation Epithelium at wound margins regenerates and migrates towards the injured tissue cells
)
Day 3-30
Fibrous granulation tissue is fully developed Collagen deposition occurs as debris is being removed Myofibroblasts form
Several Months
Complete blanching of scar; Fully healed wound
