Reproductive System

Female Sex Hormones

Anatomy of Sperm

head- contains nucleus with DNA inside

acrosome- anterior portion of head, contains enzyme needed for penetration the female egg

midpiece- contains mitochondria that provide energy, ATP, for journey through the female reproductive system

flagella (tail)- only human cell with a tail

Male Reproductive System

Ductus system- delivery of male gamete (sperm)

Accessory organs- secondary sex organs

epididymis

ductus deferens (vas deferens)

urethra

seminal vesicle

prostate gland

External genitalia

penis

scrotum

Testes

Covering of testis

each lobule contains one to four seminiferous tubules

tightly coiled structures

function as sperm-producing factories

sertoli cells- provide nutrients and supportive function

empty sperm into the rete testis

sperm travels through the rete testis to the epididymis

interstitial (leydig) cell

found surrounding seminiferous tubules produce androgens

tunica albuginea

septa

outer shell or the capsule surrounding the testes

extention of the capsule that extend into the testis and divide it into lobules

Spermatogenesis

production of sperm cells

begins of sperm cells

takes about 64 to 72 days

produces several hundred million sperm each day

spermatoza move to epididymis for further maturation and storage

Gonads

primary sex organ which produces specialized cells called gametes

testes- male primary sex organ

ovaries- female primary sex organ

produces ova or eggs (female gametes)

produces sperm (male gametes)

Male Sex Hormones

Inhibin

released by the testes when high levels of testosterone are present to release stimulate hypothalamus to release gonadotropin inhibiting hormone to stop production of LH and FSH

Lutinizing Hormone (lH)

stimulates seminiferous tubules to secrete testosterone

Follicle Stimulating Hormone (FSH)at puberty stimulates sertoli cells for sperm production and maturation

release by anterior pituitary gland in the brain

release by anterior pituitary gland in the brain

Gonadotropin Releasing Hormone (GnRH)

released by hypothalamus in the brain to stimulate anterior pituitary gland to release LH and FSH

triggered by low levels of testosterone

controlled by negative feedback

Testosterone

stimulates reproductive organ development and sex drive

secondary sex characteristics

deepening of voice

increased hair growth

enlargement of skeletal muscles

thickening of bones

Gonadotropin Releasing Hormone (GnRH)

released by hypothalamus in the brain to stimulate anterior pituitary gland to release LH and FSH

Follicle Stimulating Hormone (FSH)

stimulates the development annd maturation of primary follicle into secondary follicle

Luteinizing Hormone (LH)

spike of hormone will trigger ovulation of the most mature follicle (only one)

Inhibin

decrease release of FSH by anterior pituitary gland

Estrogen

primary female sex hormone released by developing follicle

low levels causes release of FSH

high levels cause release of LH and GnRH

Thickening of uterine wall

breast development

skeletal muscle growth and bone thickening

widening of hips

appearance of bodily hair

increase in fat beneath the skin

onset on menses

Progesterone

triggers suppression on the hypothalamus from releasing GnRH

Estrogen, inhibin, and progesterone all released by corpus luteum (shell left after release of muture oocyte from the mature follicle)

stimulates the development and growth of the lining of the uterine wall to get ready for implantaion

Bacterial STDs

symptoms

no symptoms

sores

blood in urine

burning sensation during urination

rashes and itching

bumps

warts

unusual discharge

also called sexually transmitted infections (STI)

STDs are infections which are capable of being spread from person to person through sexual intercourse or oral-genital contact in non-sexual ways

Chlamydia

most common STD

caused by bacteria

can be cured by antibiotics

male symptoms

female symptoms

discharge from penis and/or burning during urination

burning and itching around urethral openis of penis

pain and swelling in testicles

low grade fever due to inflammation of testicles or epididymis

no symptoms

white or grey vaginal discharge or burning during urination

lower pelvis or abdominal pain (pelvic inflammatory disease or PID)

low grade fever due to infection as infection progresses

Gonorrhea

caused by a bacteria

spread from close sexual contact

can be spread from mother to child during child birth

can spread to other unlikely parts of body (mouth, throat, rectum)

male symptoms

yellow or white discharge from penis

burning/pain while urinating

frequent urination

swollen testicles

female symptoms

yellow or white discharge from vagina

burning or pain when urinating

bleeding between periods and heavier or more painful periods

nausea or fever

can be cured with antibiotics

Syphilis

goes symptom-less for years

caused by bacteria can be cured with antibiotics in early stages

spread from person to person through direct contact with syphilis sore, semen, or vaginal fluids

sores appear anywhere semen and vaginal fluids comes in contact with such as genitals, anus, rectum, lips, mouth, and eyes

symptoms go through various stages

early symptoms

painful sores at point of contact called chancres

chancres can turn to copper-colored skin rashes on hand and feet or cover entire body

later symptoms

fever, headache, loss of appetite

symptoms disappear but bacterium remains in body and travels to other organs including brain, eyes, heart etc., causing organ damage

can lead to death in 10-30 years due to heart attack or brain damage

Female Reproductive System

Ovaries

primary sex organ

female gonad, paired, almond-shaped organ on either side of uterus

fibrous capsule is called tunica albuginea

outer cortex houses developing female gamete, the oocyte, within follicles

Support for ovaries

Suspensory ligaments- secure ovary to lateral walls of pelvis

Ovarian ligament- attach to uterus

Broad ligament- encloses suspensory ligament

Oogenesis

process of producing ova or egg cells

total supply of eggs are present at birth

ovulation or ability to release eggs begins at puberty

reproductive ability ends at menopause

oocytes are matured in developing ovarian follicles

matures oocyte are called Graafian follicle just before being released

Ductus system

uterine (fallopian) tube

uterus

vagina

External Genitalia

mon pubis

labia

clitoris

Uterine (Fallopian) tubes

receive the ovulated oocyte

fertilization occurs inside the uterine tube

provide a site for fertilization

attached medially to the uterus

Regions of the uterine tube

infundibulum- open end is funnel-shaped (cone-shaped), not directly connect to ovary

fimbriae- finger-like projections at the distal end that draws the ovum into the uterine tube

cilia inside the uterine tube slowly move the oocyte towards the uterus (takes 3-4) days

Uterus

located between the urinary bladder and rectum

hollow organ

functions of the uterus

receive a fertilized egg

retain the fertilized egg

nourishes the fertilized egg

Regions of uterus

body- main portion

fundus- area where uterine tube enters

cervix- narrow outlet that protrudes into the vagina or opening into the uterus

Walls of uterus

endometrium

inner layer

allows for implantation of a fertilized egg

sloughs off if no pregnancy occurs during menses

myometrium

perimetrium

outer visceral peritoneum (covering of abdominal organs)

middle layer of smooth muscle

Vagina

Mammary glands

found in both sexes but ceases to develop in males

modified sweat glands

responsible for milk production after birth by the hormone, prolactin

milk exits through the nipple

areola is the colored portion surrounding the nipple

extends from cervix to exterior of body (vaginal opening)

behind bladder and in front of rectum

serves as a birth canal

receives the penis during sexual intercourse

hymen- partially closes the vagina until it is ruptured

External Genitalia

also called the vulva

mons pubis- fatty pad overly the pubic area covered by pubic hair after puberty

labia- skin folds around the vaginal opening

labia majora- outer fold

labia minora- inner fold

vestibule

enclosed by labia majora

contains the opening to the urethra and greater vestibular gland or Bartholin's gland (produce mucus to reduce friction during sexual intercourse)

clitoris

contains erectile tissue

corresponds to male penis

Female reproductive cycle

reproductive cycle

typical cycle run 24-35 days, 28 on the average

two cycles:

ovarian cycle

uterine (menstrual) cycle

occurs in the ovaries leading to the maturartion and ovulation of the mature oocyte

made up of follicular phase (before ovulation) and luteal phase (after ovulation)

occurs in the uterus to prepare the uterus for implantation of the fertilized ovum

made up of menstrual phase, proliferative phase (before ovulation), and secretory phase (after ovulation)

ovarian cycle

follicular phase

day 1-14

extends from the beginning of menstruation until ovulation

FSH causes follicular cells develop into primary follicle

follicular cells secrete estrogen to become secondary follicle

luteal phase

day 15-28

when follicle expels the oocyte, the empty shell becomes corpus luteum

corpus luteum secretes progesterone, some estrogen, and inhibin which suppresses FSH

in absence of pregnancy, corpus luteum becomes corpus albicans causing decrease in progesterone and estrogen

if pregnancy occurs, the corpus luteum continues to secrete progesterone and estrogen

uterine/menstrual cycle

menstruation phase

day 1-5

decline of estrogen and progesterone cause the spiral arteries to constrict, cells become ischemic and die, and are sloughed off or shed

bleeding lasts for 3-5 days

proliferative phase

day 6-14

estrogen stimulates growth of blood vessels of the endometrium causing it to double in thickness

thickening of endometrium allows ovulated egg to be caught to cause implantation

secretory phase

day 15-28

uterine glands enlarge and secrete nutrients to sustain the embryo until implantation occurs

n response to rising levels of progesterone by the corpus luteum, the uterus becomes ready for pregnancy

if pregnancy does not occur, toward the end of phase, ZLH levels drop due to high levels of progesterone

progesterone levels drop following decline in LH, leading into menstrual phase

Viral & Parasitic STDs

Herpes

caused by a herpes virus

cannot be cures but can be treated with antiviral medication

males symptoms

female symptoms

small sores or cluster of blisters on penis

blisters in or around the vagina

fever and headaches

Genital/Veneral Warts

approximately 5.5 million new cases in U.S.

20 million people currently infected in U.S.

caused by the human papilloma virus (HPV)

no cure but prevent through vaccination

symptoms same for males and females

associated with cervical cancer in females

symptoms:

warts look like tiny cauliflowers

may cause itching, brining but most often do not cause pain

warts may be not detected in females because they are located internally

Acquired Immune Deficiency Syndrome (AIDS)

cause by human immunodeficiency virus (HIV)

spread through sexual intercourse but can be passed by sharing needles or from mother to baby through child birth or breast feeding

no cure, only treatment

symptoms:

no symptoms until immune system is activated

fever, fatigue (flu-like symptoms)

swollen lymph node

weight loss

opportunistic infection

Pubic Lice or Crabs

caused by a parasite that look like "crabs"

usually located around pubic area around the hair but can be found in axilla, eyelashes, and mustaches

spread through direct contact with lice even through bedding or clothing

symptoms:

a terrible, persisting itch around area

treated with shampoo or cream

Trichomoniasis

cause by a tiny parasite

most commonly in women

can be transmitted to baby during delivery

female symptoms:

itching and burning at the opening of vagina and vulva

painful frequent urination

heavy, unpleasant, frothy, greenish, yellow discharge

male symptoms:

no symptoms

or discomfort in urethra or inflamed head of penis

treatment through oral medication

Functions of Reproductive System

Female accessory organ

prepare for implantation (ovum adheres to the endometrium, inner lining wall of the uterus) and prepares for developing during pregnancy

delivery of the fetus during child birth

nurtures the baby after birth

Female reproductive system

functions in production of female gamete (ovum or egg) and preparation for support of developing embryo during pregnancy

Male accessory organ

produces and secretes seminal fluids

various ducts and tubes which act as delivery system for the male gamete

external genitalia made up of penis and scrotum

Male reproductive system

functions to produce and disseminate large quantity of male gamete

Reproductive system

reproduction- process by which new individuals (offspring) of a species are produced

sexual reproduction- reproduction involving two (male and female) parents

fertilization- fusion of egg and sperm produces a zygote

Penis

tubular organ through which distal portion of urethra passes

conducts urine to exterior

delivers semen into female reproductive tract

regions of penis

root- attached to body wall

shaft (bod)- free, movable portion of penis, contains three cylindrical columns of erectile tissue

glands penis (enlarged tip)- contains urethral opening

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