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Asthma (Precipitants (Emotion, Allergens, Exercise, Infection, Cold air,…
Asthma
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Investigations
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ABG: normal or low PaO2 and low CO2 in acute attack, high CO2 in respiratory failure
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Skin prick test to identify allergens and ask about pets, carpet, duvet, job (symptoms may remit at weekend)
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If there are many nights of disturbed sleep a weak, this signifies severe asthma
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Pathophysiology
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Airway Narrowing
Mucosal inflammation, caused by mast cell and basophil degranulation
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Inflammation
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Mast cells, eosinophils, T lymphocytes and dendritic cells are increased in bronchial wall + mucus membranes
Classification
Extrinsic
Reaction to common inhaled allergens e.g. dust mite, pollen
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Definition
Recurrent episodes of dyspnoea, cough and wheeze caused by reversible airway obstruction