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Motor Neurone Disease (Treatment (Dysphagia: blend food, NG tube,…
Motor Neurone Disease
Treatment
Dysphagia: blend food, NG tube
Spasticity: exercise, diazepam
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Palliative care: opioids, non-invasive ventilation
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Clinical Patterns
Progressive Bulbar Palsy
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LMN lesion of tongue - leads to flaccid, fasciculating tongue
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Speech is quiet, hoarse or nasal
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Investigations
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Suspect MND in anyone >40 yrs with stumbling spastic gait, foot drop, weak grip and shoulder abduction
Signs
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LMN
Fasciculation of tongue, abdomen, back, thigh
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Definition
A cluster of neurodegenerative diseases, characterized by selective loss of neurones in the motor cortex, cranial nerve nuclei and anterior horn cells