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Psychosis (CLINICAL (SIGNS + SYMPTOMS (Hallucinations (auditory, tactile,…
Psychosis
CLINICAL
disorder of the mind
loss of contact with reality
altered perception
social, emotional, communicative & cognitive responses altered
No single factor alone will cause
is a combination
SIGNS + SYMPTOMS
Hallucinations
auditory
tactile
alfactory
Thought disorganisation
Agitation + aggression
PRIMARY ILLNESSES
Schizophrenia
Substance abuse
schitzoffective disorder
SECONDARY ILLNESS
Thyroid conditions
Substance abuse
IMPACTED BY ...
GENETICS
increase risk of development
close relative
illnesses associated with psychosis can run in families
TRAUMA + STRESS
increase risk of developing
could trigure acute episodes / relapse
SOCIETY
stigma + discrimination
perception of dangerous
increase social interaction + decrease help seeking
peer pressure
drug + alcohol triggure relapse
CULTURE
impact interpretation / meaning
impact seeking & knowledge
diagnosis b/t cultures = different
impact interactions
Mesacorticle pathway
VTA neurons communicate with PFC
VTA releases reduced dopamine levels across synapse to PCF
low dopamine = negative symptoms
volition + flattening affect
The Science
changes in the brain cause person to experience psychosis
effects
limbic system = VTA - NAC
Mesolimbic pathway
prefrontal cortex = VTA - PFC
Mesacortical Pathway
altered state of mind
ADOLESCENCE
more likely to develop
changes in lifestyle + development + stress
more susceptible if family history
drug abuse
PREGNANCY
some antipsychotics may cross through placenta
risks weighed to determine stop or continue medication
GENDER
Males more likely than females
Mesolimbic pathway
VTA releases excess dopamine across synapses to NAC
increase dopamine = positive symptoms
hallucinations + delusions
VTA neurons communicate with NAC
