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OBESITY DRUGS (ORLISTAT (SIDE EFFECTS (fatty stools or discharge, headache…
OBESITY DRUGS
ORLISTAT
MECHANISM OF ACTION
Orlistat inhibits the absorption of dietary fats by forming a covalent bond w/ the active serine residue site of the gastric and pancreatic lipases w/in the lumen of the stomach and small intestine.
thus preventing the hydrolysis of dietary fat in the form of triglycerides into absorbable free fatty acids and monoglycerides.
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PREDNISONE
CONTRAINDICATIONS
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Concurrent admin of live or live attenuated vaccines (in patients receiving immunosuppressive doses).
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MECHANISM OF ACTION
Prednisone decreases inflammation through inhibition of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability.
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SIBUTRAMINE
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MECHANISM OF ACTION
Sibutramine inhibits the reuptake of norepinephrine and serotonin, and to a lesser extent, dopamine.