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HORMONES AND REPRODUCTIVE DRUGS (CLOMID/ CLOMIPHENE (NURSING CONSIDERATION…
HORMONES AND REPRODUCTIVE DRUGS
CLOMID/ CLOMIPHENE
NURSING CONSIDERATION
CONTRA INDICATIONS
liver disease
ovarian cyst
pregnancy
abnormal uterine bleeding of undetermined origin
Hypersensitivity or allergic to clomiphene citrate
ROUTE FOR ADMINISTRATION
orally
STORAGE
protect from heat and excessive humidity
store in an airtight container
store at controlled room temperature of 15 to 30 degrees celcius
SIDE EFFECTS
headache
bloating
blurred vision
ovarian hyper stimulation syndrome
nausea
INDICATIONS
Treatment for ovulatory dysfunction
polycystic ovary syndrome
MECHANISM OF ACTION
clomid compete with oestrogen for binding sites at the hypothalamic level, the FSH, LH and gonadotropin secretion is increased resulting in ovarian follicle maturing followed by the pre ovulatory LH, ovulation and development of corpus luteum
PROGESTERONE
INDICATIONS
treatment of dysfunctional uterine bleeding
treatment of amenorrhea
Prevention of endometrial hyperplasia associated with conjugated estrogen therapy
MECHANISM OF ACTION
its an obligatory steroid mediator of pregnancy. it induces transformation of uterine endometrial cells so that implantation of the developing blastocyte is facilitated. it then suppresses myometric activity aiding in retention of the embryo during implantation and growth prior to normal parturition.
NURSING CONSIDERATION
CONTRA INDICATION
abnormal vaginal bleeding
hepatic disease or hepatic dysfunction
liver problem
ROUTE FOR ADMINISTRATION
orally
Intramuscular
SIDE EFFECTS
drowsiness or insomia
breast enlargment
fatigue
weight gain
premenstrual syndrome
Stomach upset
STORAGE
keep away from sunlight
store in an airtight container