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L10 - Chlamydia, Mycoplasma, Anaerobes Describe the general properties…
L10 - Chlamydia, Mycoplasma, Anaerobes
- Describe the general properties of genera in the family Chalmydiaceae
- List the human pathogenic genera species within the family
- Describe the diseases caused by C.trachomatis and how they relate to different serovars
- Describe he illnesses produced by species in the genus Chlamydophila
- Describe the general properties of genera in the family Mycoplasmataceae
- Describe the illness caused by M.pneumonia
- List the species of Mycoplasma/Ureaplasma implicated in human disease
- Discuss why it is difficult to attribute definite disease causality to the genital mycoplasmas.
- Name species of Mycoplasma for which tenuous or definite disease causality has been estabilished; name diseases
- Discuss briefly the meaning of anaerobiasis as it applies to bacteria.
- Recognise the names of typical anaerobic bacteria
- Describe the difference between endogenous and exogenous anaerobic infections.
- Give examples of endogenous and exogenous anaerobic infections.
Family Chalmydiaceae
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RESPIRATORY INFECTIONS
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ANIMAL INFECTIONS
Chlamydophila psittaci
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Psittacosis/ornithosis
Flu-like => non-specific; fever, sore throat => heptosplenomegaly/large lymph nodes
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Family Mycoplasmataceae
- smallest free living microorganisms
- lack a cell wall => difficult for antibiotics to target => can't be seen on gram stain (too small anyway)
- 6 species implicated in human diseases
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Genital Mycoplasmas
Many are commensals of the genital tract
Population size = proportionate to sexual activity
Difficult to attribute definite links between these bacteria and disease, because their role as pathogens is UNCERTAIN => they are known commensals of genital tract
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Anaerobic bacteria
Ubiquitous members of commensal;
=> Bowel flora
=> Oropharynx flora
=> Vaginal flora
=> Skin flora
Will not gro on surface of blood agar UNLESS in anaerobic conditions
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Anaerobic Infections
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Exogenous Infections
Sustained from wounds/injuries (e.g. bit wounds)
e.g. Clostridium tetani, perfingens
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