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Drugs of the thyroid gland (Desicated thyroid (Nursing considerations…
Drugs of the thyroid gland
Desicated thyroid
Indications
Hypothyroidism
Hashimoto's thyiroditis
Fibromyalgia
Mechanism of Action
Binds to DNA to modulate gene expression
Either by stimulating on inhibiting transcription
Nursing considerations
Contraindications
Hypopituitarism
Acute myocardial infarction
Osteoporosis
Diabetes Melitus
Side effects
Decreased appetite
Heart palpitations
Brittle nails
Weight gain
Storage
15 to 30 degrees celcius
Away from heat and moisture
Route of Administration
Orally
Liothyronine
Indications
Hypothyroidism
Nontoxic goitre
Myxedema coma
Mechanism of Action
Binds to nuclear thyroid receptors
Which bind to thyroid hormone response element of gene
Thus liothyronine induces gene expression
Required for normal growth and development
Nursing considerations
Contraindications
Hypersensitivity to liothyronine
Hypertension
Hyperthyroidism
Thyrotoxicosis crisis
Side effects
Nausea
Menstrual changes
Diarrhea
Irritability
Storage
Refrigerator 2 to 8 degrees celcius
Away from heat and moisture
Route of Administration
Orally
Intraveneously