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Drugs of the thyroid gland (Levothyroxine (Indications (Hypothyroidism,…
Drugs of the thyroid gland
Levothyroxine
Indications
Hypothyroidism
Grave's disease
Myxedema coma
Thyroid tumurs
Mechanism of Action
Converted to it's metabolites, T3
T3 binds to receptor protein in the nucleus
Causing metabolic effect through DNA transcription and protein synthesis
Nursing considerations
Contraindications
Hyperthyroidism
Hypersensitivity to levothyroxine
Acute myocardial infarction
Pregnancy
Side effects
Anxiety
Chest pains
Diarrhea
Heart rhythm disturbance
Storage
15 to 30 degrees celcius
Away from heat, moisture and light
Route of Administration
Orally
Intraveneously
Liotrix
Indications
HYypothyroidism
Thyroid cancer
Goitre
Mechanism of Action
Enhance oxygen consumption by most tissues in the body
Increases basal metabolic rate
Increases metabolism of carbohydrates, lipids and proteins
Nursing considerations
Contra indications
Hypertension
Myocardial infarction
Thyrotoxicosis
Uncorrected adrenal insufficiency
Side effects
Hair loss
Bone pain
Diarrhea
Headache
Storage
Refrigerator 2 to 8 degrees celcius
Away from light
Keep out of children's reach
Route of administration
Orally