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L3 - ANTIBIOTICS 1:
(1) Review and outline the four broad mechanisms by…
L3 - ANTIBIOTICS 1:
(1) Review and outline the four broad mechanisms by which bacteria can be resistant to antibiotics.
(2) Explain why 80% or more of S. aureus strains are resistant to penicillin.
(3) Name 2 penicillins and two cephalosporins that are resistant to staphylococcal beta lactamase.
(4) Explain the mechanism of resistance of MRSA to beta-lactam antibiotics.
(5) Discuss the use of and mechanism of beta-lactamase inhibitors and name an oral and parenteral drug
combination in which these are used.
(6) Name 4 oral antibiotics, each from a different class, which may have activity against MRSA.
(7) Name an IV antibiotic used to treat serious MRSA infections.
(8) Name an infection where formal MIC testing is done on the causative organism and discuss why.
(9) Explain why a 10 day course of antibiotics is used in the treatment of streptococcal pharyngitis. Name
two drugs used for this purpose
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