Please enable JavaScript.
Coggle requires JavaScript to display documents.
CR - Lung Tumours (ii) (small cell carcinoma (+ve neuroendocrine markers…
CR - Lung Tumours (ii)
-
Tissue Dx
-
essential for tx
discriminates non-small cell + small cell (staged as either limited or extensive, non-surgical tx, chemo + prophylactic cranial irradiation as brain = common met site)
-
-
-
adenocarcinoma
-
-
-
-
-
form glands, prominent nucleoli
TTF1 (thyroid transcription factor 1) +ve (specific in lung, -ve in mets)
-
Molecular advances
-
allows for targetted Tx, esp in adenocarcinoma (hence do molecular testing)
-
-
-
-
-
-
small cell carcinoma
-
-
-
-
necrosis, prominent mitosis
-
-
-
-
-
-
ECOG status
-
lung cancer patients often have comorbidities (COPD, heart disease - cor pulmonale)
-
1 - light work, not strenuous
-
3 - limited selfcare, confined to bed/chair over 50% of awake hrs
4 - completely disabled, totally confined
-
-