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The Lymphatic System (Spleen (Contains 2 types of Tissues: (white pulp…
The Lymphatic System
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Lymph Function
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Removal and destruction of potentially harmful foreign particles from the lymph (accomplished through phagocytosis by macrophages)
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Thymus
each lobule contains an outer cortex filled with densely packed lymphocytes around a central medulla filled with swirled epithelial cells (Hassall's Corpuscles)
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Functions:
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the epithelial cells secrete thymosin-stimulates further maturation of T cells after they leave the thymus and migrate to other lymphatic tissues
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soft, bilobed organ located within the mediastinum
Lymph Formation
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as protein concentration in interstitial spaces increases, its pressure increases
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14.2 Major Functions
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Distribution of hormones, nutrients, and waste products from their tissues of origin to the general circulation
Production, maintenance, and distribution of lymphocytes
Lymphatic Vessels
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lead to lymph nodes as "afferent" LVs, leave lymph nodes as "efferent" LVs, and then merge into lymphatic trunks
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Lymphatic Tissue
Lymph Nodules
when it is not encapsulated, it is called diffuse lymphatic tissue (found in submucosa of mucous lining)
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Collecting Ducts
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Thoracic (left lymphatic)- drains the remaining 75% of the body's lymph; between left subclavian and left internal jugular veins
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II. Lymphatic Pathways: pathways begin as lymphatic capillaries and come together to make afferent lymphatic vessels
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14.2 Lymphatic Vessels
Lymphatic capillaries
are associated with anchoring filaments, which serve as an important function during edema
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Lymph Nodes
Structure
size is usually less than 2.5 cm, and shape is bean-like, with blood vessels, nerves, and efferent lymphatic vessels attached to the indented region (hilum)
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Lymph nodes are located along lymphatic pathways, contain lymphocytes and macrophages, which destroy invading microorganisms
Outer region= cortex; contains germinal centers of densely packed B cells (+microphages) in lymphatic nodules or follicles
Inner region= medulla; contains T cells (macrophages and plasma cells) arranged as medullary cords (spaces through which lymph flows)