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L8 - GRAM NEGATIVE BACTERIA P2 Describe the clinical significance of the…

- - - - Common in the tropics
      - Ulcerative genital lesions
      - Enlarged inguinal lymph nodes
    - - Urethritis => purulent urethral discharge
      - => Cervicitis = purulent discharge
        => Salpingitis (inf. fallopian tubes)
        => Pharyngitis/anorecal inf.
        => Bacteraemia
      - => Opthalmia neonatorum => BLINDNESS
        
        Born through inf. birth canal
- - - - Brucella abortus (cattle)
      - Brucell melitensis (sheep, goats)
      - Brucella canis (canis)
      - Brucella suis (swine)
  - - - Initial lesion => papule/putsule/vesicle => lyphadenopathy
- - - - Abdominal cramping
      - Fever
      - Self limiting diarrhoea (commonest cause locally)
- - - - Haemophilus influenzae type B
        
        Epiglottitis => laryngeal obstruction
        
        Septicaemia => Meningitis (purulent = pus)
        
        S.pneumoniae + H. inluenzae TB + N. meningitidis = Purulent meningitis
- - - - Purpuric rash (appears like bruise = techiae in early stages) => Gangrene