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parathyroid drugs-calcitriol (SIDE EFFECTS (metallic taste, nausea,…
parathyroid drugs-calcitriol
CONTRAINDICATIONS
Drugs should be used in pregnancy only if the benefit to the mother clearly outweighs the potential risk to the fetus
Drug should not be used in the presence of any known allergy
SIDE EFFECTS
metallic taste
nausea
vomiting
dry mouth
constipation
anorexia
bone pain
STORAGE CONDITIONS
Store in clearly labelled containers
keep out of reach of children
store at room temperature
MECHANISM OF ACTION
A vitamin compound that regulates the absorption of calcium and phosphate from the small intestine.
Calcitriol's lifespan in the body is measured in hours, unlike its precursor calcifediol whose lifespan is measured in weeks.[22] Calcitriol is inactivated by further hydroxylation to form 1,24,25-trihydroxyvitamin D, calcitroic acid. This occurs through the action of the CYP24A1 24-hydroxylase.[23] Calcitroic acid is more soluble in water and is excreted in bile and urine.
INDICATIONS
Management of hypercalemia in patients on chronic renal dialysis
management of hypercalcaemia associated with hypoparathyroidis
NURSING CONSIDERARTIONS
to give the patient their medication on the right dose
nurse is to asses any allergies that the patient may present with.
should the patient be found that she is pregnant the doctor is to be notified and patient is to be weighed