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Individual immunisations (MMR (Administration IM (upper arm,…
Individual
immunisations
DTaP/IPV/HiB/HepB
Administration
IM in anterolateral thigh (reduced local reactions)
Deep SC if bleeding disorder (reduced bleeding)
AEs
Malaise, fever, rash
Febrile seizures, anaphylaxis (rare)
Constituents
DTaP:
inactivated diphtheria toxin, tetanus toxin, pertussis antigens
IPV:
inactivated polio virus
HiB:
capsular polysaccharide
HepB:
HBsAg
CIs
Acute febrile illness
Previous anaphylactic reaction to vaccine/constituents
Indication
8w, 12w, 16w
Rotavirus
SEs
Diarrhoea, irritability, vomiting, flatulence, regurgitation,
fever, anorexia
CIs
Acute febrile illness
Previous anaphylactic reaction to vaccine/constituents
Severe combined immunodeficiency (SCID)
Aged >6m
Administration
Oral
Constituents
Live attenuated rotavirus
Indication
8w, 12w
PCV
Constituents
PCV-13: conjugate vaccine (13 capsular polysaccharides)
PCV-23: conjugate vaccine (23 capsular polysaccharides)
Administration
SC (anterolateral thigh in children; upper arm/thigh adults)
SEs
Vaccination site reactions, fever, irritability, anorexia, insomnia
CIs
Acute febrile illness
Previous anaphylactic reaction to vaccine/constituents
Indication
PCV-13: 8w, 16w
PCV-23: 65 years
BCG
SEs
Headache, fever, lymphadenopathy, injection site reactions
Administration
Intradermal, lateral upper arm (insertion of deltoid) to avoid keloid
Constituents
Live attenuated BCG (M bovis)
Indication
Parents/grandparents from high risk country
Occupational risk e.g. HCPs
CIs
Acute febrile illness
Confirmed anaphylactic reaction to vaccine/constituents
Previous BCG vaccination
Previous TB
Previous +ve Mantoux test
Immunosuppressed (especially HIV+)
MMR
Administration
IM (upper arm, anterolateral thigh)
SEs
Malaise, fever, rash, parotid swelling
Febrile seizures (rare)
Constituents
Live attenuated measles, mumps and rubella
CIs
Acute febrile illness
Confirmed anaphylaxis to vaccine/constituents
Pregnancy
Immunosuppressed
Indication
1y and 3y 4m
Caution
Egg allergy
Influenza
Constituents
Live attenuated influenza virus (LAIV)
Inactivated influenza virus
Administration
Nasal spray (LAIV)
OR IM (inactivated vaccine)
Indication
LAIV:
school-age children
Inactivated:
adult risk groups (immunocompromised,
heart/lung/renal/liver disease, etc.)
AEs
Pain swelling, redness at site
Low grade fever, malaise, fatigue, headache, myalgia, arthralgia
CIs
Acute febrile illness
Anaphylactic reaction to vaccine/constituents
Severe immunocompromise (LAIV)
Meningitis
Administration
IM in upper arm/anterolateral thigh (reduced local reactions)
Men B in LEFT THIGH specifically!
Deep SC if bleeding disorder (reduced bleeding)
AEs
Pain, swelling, redness at site, mild fever
Crying, irritability, drowsiness, D+V, anorexia (toddlers)
Headaches, myalgia, drowsiness (older children/adults)
Indication
MenB:
8w, 16w, 1y
Hib/MenC:
16w
MenACWY
14y
CIs
Acute febrile illness
Confirmed anaphylactic reaction to vaccine/constituents
Constituents
MenB:
conjugated MenB capsular proteins
MenC:
conjugated MenC capsular proteins
Hib/MenC
: conjugated HiB and MenC capsular proteins
MenACWY:
conjugated capsular proteins MenACWY
HPV
Administration
IM in upper arm/anterolateral thigh (reduced local reactions)
Deep SC if bleeding disorder (reduced bleeding)
SEs
Injection site pain, stinging, redness, headache,
myalgia, fatigue, fever
Indication
Girls 13-14y
CIs
Acute febrile illness
Confirmed anaphylactic reaction to vaccine/constituents
Constituents
Quadrivalent viral coat proteins (HPV 6, 11, 16, 18)
HepB
(monovalent)
Constituents
Monovalent HBsAg (HepB)
Administration
IM in upper arm/anterolateral thigh (reduced local reactions)
Deep SC if bleeding disorder (reduced bleeding)
Indication
Babies born to HepB+ mother
Adults at occupational/lifestyle risk e.g. HCPs
SEs
HepB: pain/redness at site, fever, rash
Hexavalent: fever, pain, swelling, redness
CIs
Acute febrile illness
Confirmed anaphylactic reaction to vaccine/constituents
VZV
Administration
IM/SC in deltoid (IM preferred)
SEs
Erythema, pain, swelling, pruritus
Constituents
Live attenuated VZV
CIs
Acute febrile illness
Confirmed anaphylactic reaction to vaccine/constituents
Immunosuppression
Pregnancy
Indication
Chickenpox:
non-immune persons at risk
Shingles:
70y
DTaP/IPV
Administration
IM (upper arm)
SEs
Malaise, fever, rash
Anaphylaxis (rare)
Constituents
DTaP:
inactivated diphtheria toxin, tetanus toxin, pertussis antigens
IPV:
inactivated polio virus
CIs
Acute febrile illness
Previous anaphylactic reaction to vaccine/constituents
Indication
3y 4m
Td/IPV
Constituents
Td:
inactivated diphtheria toxin, tetanus toxin
IPV: inactivated polio virus
Administration
Upper arm
Indication
14y
SEs
Malaise, fever, rash
Anaphylaxis (rare)
CIs
Acute febrile illness
Previous anaphylactic reaction to vaccine/constituents