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drugs of thyroid gland [hypothyroidism] (Thyroid Desisiccated (sides…
drugs of thyroid gland [hypothyroidism]
Levothyroxine
sides effects
hair loss
sweating
tremors
tachycardia
palpitations and allergic skin reaction
contraindications
suppressed levelof thyroid stimulating hormone patient
mechanism of action
levothyroxin increases the metabolic rate of body tissue, increasing oxygen consumption, respiration, heart rate and growth and maturation.
indications
as a replacement therapy in hypothyrodism
suppression of thyroid stimulating hormone level.
used in treatment for myxoedema coma and thyrotoxicosis
Liothyronine
sides effects
change in appetite
confusion
decrease urine output
irritability
chest pain
Storage conditions
cool ,dry place and away from sunlight
store in tight containers
keep out of reach of children
mechanism of action
it also increases the metabolic rate of body tissue, by increasing oxygen consumption, respiratory and heart rate, rate of fats, protein and carbohydrate metabolism and growth as well as maturation.
indications.
it is used as replacement therapy in hypothyroidism
treatment of thyrotoxicosis
suppression of thyroid stimulating hormone.
contraindications
use with caution for any known allergies
hypersensitivity to any components of liothyronine sodium tablets
Thyrotropine alpha
sides effects
headache
dizziness
hypersensitivity reactions (hives, rash, itching, flushing and respiratory symptoms
weakness
temprary flu-like symptoms (fever, chillis, shivering, muscle or joint pain.
contraindications
pregnant women
Breastfeeding mothers
storage condition
Avoid direct sunlight
mechanism of action
thyrotropin alpha binds to the thyropin receptors found on any residual thyroid cells or tissues, this stimulates radioactive iodine uptake for better radiodiagnostic imaging.
indications
it is used for the detection of residual or recurrent thyroid cancer.
Thyroid Desisiccated
sides effects
leg cramps
sensitivity to heart
vomiting
nausea
contraindications
hypersensetivity
cardiac failure
must be used with caution in patients with addinson's disease
mechanism of action
this drug increases the metabolic rate of body tissues, increasing oxygen consumption, respiratory and heart rate, amount of fats and protein.
indications
for thyroid stimulating hormone suppression, in treatment and prevention of eurothyrid goiters and management of thyroid cancer
also plays a huge role in treatment of thyrotoxicosis.
storage conditions
store away from direct sunlight
store in a clearly labelled container
store out of treach of children
store in a cool dry place
route of administration
adults, 65mg/d PO
Peads, 16mg/d PO for two weeks, followed by 32mg/d for two more weeks then 65mg/d