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Chronic Kidney Disease (Signs (Polyneuropathy: weakness, pins and needles,…
Chronic Kidney Disease
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Signs
Polyneuropathy: weakness, pins and needles
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Renal osteodystrophy: Osteomalacia, osteoporosis. Due to phosphate retention and impaired production of 1,25 dihydroxyvitamin D. Leads to decrease in serum calcium and increase in PTH secretion
MI, cardiac failure, stroke
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Fluid overload: oedema, high BP
Investigations
Creatinine
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The higher the GFR, the lower the creatinine
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Bloods: normochromic normocytic anaemia, glucose (DM)
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Treatment
Anaemia: replace iron, B12, folate. Consider giving recombinant human Epo
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