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Mumps (Differentials (Metabolic DM Liver cirrhosis Uraemia, Drugs …
Mumps
Differentials
Metabolic
DM
Liver cirrhosis
Uraemia
Drugs
Thiazide diuretics
Trauma
Salivary stone obstruction
Neoplastic
Cyst
Tumour
Infection
Viral: EBV, parainfluenza, influenza, adenovirus, coxackivirus, parvovirus B19, HIV
Bacterial: s aureus, TB
Autoimmune
Sarcoidosis
Sjorgren's syndrome
GPA
Complications
ENT
Hearing loss (transient)
CNS
Cerebellar ataxia
Facial palsy
Transverse myelitis
GBS
Cardiovascular
ECG change (ST dep, T wave inv, prolonged PR)
Myocarditis and dilated CM (rare)
Infection/inflammation
Parotitis
Pancreatitis
EO, oophritis
Encephalitis (rare)
Thyroiditis, mastitis, hepatitis, prostitis (all rare)
Pathophysiology
Transmission
Respiratory droplets, saliva, fomites
Mechanism
Incubation 2-3wk, infectious 1-2d before symptoms to 9d after
Infects and replicates in URT mucosa
Most people get lifelong immunity
Agent
Mumps paramxyovirus
Clinical
presentation
Asymptomatic
Common in children
Swollen parotids
Bilateral then unilateral
May be tender
Fever
Low grade
Diagnosis
Examination
Facial examination
Swollen bilateral/unilateral parotids
Tender to palpation
Investigations
Bedside
Obs (low fever)
Swabs
Saliva sample (IgM, IgG, RNA)
Semen analysis
Indication: 3m after EO mumps
to check for reduced fertilty
History
DH
Current meds, allergies
FH
Affected contacts
PMH
Vaccinations
Medical conditions, immunosuppression
SH
Living conditions, work/school
PC/HPC
Swollen face: uni then bilateral, tender,
Associated symptoms: fever, malaise, myalgia, otalgia
Signs of complications: testicular swelling, abdo pain, N+V,
meningeal symptoms, deafness
Any affected contacts
Epidemiology
Rare since MMR
Useed to be common in school-age children
Management
Conservative
Information, advice, support
Notify PHE (notifiable disease)
Self care (rest, fluids, warm/cold packs, avoid school/work for 5d)
Follow up in 1 week
Medical
Analgesia
Indication: pain, fever
E.g. paracetamol, ibuprofen
Immunisation
Indication: potential contact who's not fully immunised
E.g. MMR
CI: pregnancy, immunosuppressed
Prognosis
Usually self limiting 1-2wk
Complications rare but commoner
in adults than children
Definition
Acute viral infection
causing parotid swelling
Prevention
Vaccination
MMR vaccination