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Ankylosing Spondylitis (Signs (Progressive loss of spinal movement in all…
Ankylosing Spondylitis
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Epidemiology
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M:F = 6L1 at 16 yrs, 2:1 at 30 yrs
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Signs
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Worse at night, improves in day
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Typical patient: man <30 with gradual onset low back pain, worse at night, spinal morning stiffness, relieved by exercise
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Investigations
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X-ray: shows joint space narrowing, sclerosis, erosions, ankylosis
Treatment
TNF-alpha blockers in severe, active cases
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