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Ophthalmic drugs (Ciproflaxin (Indications. (Lower respiratory tract…
Ophthalmic drugs
Ciproflaxin
Mechanism of action
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It functions by inhibiting DNA gyrase and a type 2 topoisomerase, topoisomerase IV necessary to separate bacterial DNA, thereby inhibiting cell division.
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Aciclovir
Mechanism of action.
Is converted by viral thymidine kinase to acyclovir monophosphate, which is then converted by host cell kinases to acyclovir triphosphate (ACV-TP).
ACV-TP, in turn competitively inhibits and inactivates HSV-specified DNA polymerases preventing further viral DNA synthesis without affecting the normal cellular processes.
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Gentamicin
Mechanism of action
It is a bactericidal antibiotic that works by irreversibly binding the 30S subunit of the bacterial ribosome, interrupting protein synthesis.
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Azothromycin
Mechanism of action.
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It binds to the 50S subunit of the bacterial ribosome, thus inhibiting translation of mRNA.
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