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Immunossuppresant (Azathioprine (Indications (Rheumatoid arthritis.,…
Immunossuppresant
Azathioprine
Mechanism of action.
Inhibit synthesis
DNA
RNA
Protein
Interferes with cellular metabolism.
Inhibit mitosis
Indications
Rheumatoid arthritis.
Granulomatosis.
Crohn`s disease.
Ulcerative colitis.
Kidney transplant.
Nursing considerations
Route of administration.
Orally.
Injection.
100mg/vial.
Side effects.
Leukopenia.
Abdominal pains.
Diarrheoa
Skin cancer.
Steatorrhea.
Fever.
Bone marrow suppression.
Rash.
Contraindications.
Severe infection.
Pregnancy.
Severe anaemia.
Decreased blood platelets.
Blood clots.
Acute inflammation.
Storage
Room temperature
25 degrees.
Protect from light.
Used within 24 hours.
Cyclosporine
Indications.
Nephrotic syndrome.
Organ transplant.
Crohn`s disease.
Rheumatoid arthritis.
Mechanism of action.
Lower the activity of T-cells
Prevent mitochondrial permeability
Prevent organ rejection.
Nursing considerations.
Side effects.
Shaking.
Kidney damage.
Hypertension.
Infection.
Headache.
Nausea.
Painful gums.
Leg cramps.
Acne.
Route of administration.
Orally.
Injection
Intravenous
Contraindications.
High cholesterol.
Liver problems.
Kidney damage.
Low amount of magnesium.
Seizures.
Storage
Room temperature.
Away from sunlight.
Do not refrigerate.
Mycophenolate
Indications
Prevent organ rejection.
Mechanism of action
Reduces the action of immune system.
Nursing considerations.
Route of administration.
Orally.
Side effects.
Constipation.
Nausea.
Headache.
Stomach pain.
Appetite loss.
Storage
Room temperature.
Refrigerator.
Contraindications.
Hypersensitivity to mycophenolate.
Cancer.
Stomach bleeding.
Malignant tumor
Kidney disease.
Stage5