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Colorectal Carcinoma (Predisposing Factors (Diet low in fibre, high in…
Colorectal Carcinoma
Predisposing Factors
Diet low in fibre, high in red/processed meat
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Investigations
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Spread can be local, lymphatic, blood or transcoelomic
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Epidemiology
2nd most common cause of UK cancer deaths - 16,000 a year
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Staging
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Duke's Criteria
B - extension through muscularis mucosae, 77% 5 year survival
C - involvement of regional lymph nodes, 48% 5 year survival
A - limited to muscularis mucosae, 95% 5 year survival
D - distant mets, 6.6% 5 year survival