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GORD (Aetiology (Loss of oesophageal peristaltic function, Obesity, Hiatus…
GORD
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Pathophysiology
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Prolonged reflux may cause: oesophagitis, benign oesophageal strictures and Barrett's oesophagus
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Treatment
PPIs e.g. lansoprazole which inhibit gastric H+/K+ ATPase, blocking luminal secretion of gastric acid
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Lifestyle changes
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Reduce alcohol, hot drinks, citrus fruits, tomatoes, onions, fizzy drinks, spicy foods, caffeine
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Surgery - e.g. laparoscopic, aims to increase resting lower oesophageal sphincter pressure. Consider in severe GORD
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Symptoms
Oesophageal
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Heartburn - burning, retrosternal discomfort after meals
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