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Corticosteroid e.g Hydrocortisone (Prednisone (Indications (Arthritis,…
Corticosteroid
e.g Hydrocortisone
Prednisone
Mechanical of action
Inhibit synthesis of protein
Stimulate lipocortin production
Indications
Arthritis
Blood disorders
Skin diseases
Eye problems
Nursing considerations
Route of admission
Orally
10mg
Side effects
Loss of appetite.
Heart burn.
Insomia.
Increased sweating.
Acne.
Weakness.
Hyperglycaemia.
Contraindications
Peptic ulcer.
Osteocorosis.
Severe psychoneuroses.
Wafarin.
Nausea medications.
Aspirin.
Storage
Room temperature
20-25 degrees.
Bethamithasone
Mechanism of action
Binds to receptor protein
It stimulates the enzymes to decrease inflammatory
Induce lipocortins in macrophages
Cause negative regulation of genes
Indications
Skin inflammation.
Rash
Itching.
Nursing considerations
Side effect
Stretch marks.
Thinning of the skin.
Red bumps
Around the mouth.
Skin dryness.
Thick hair growth.
Discolouration of skin.
Acne.
Contraindication
allergic to corticosteroids.
Suppressed immune system.
Diabetes mellitus
Infective skin disease.
Skin ulcers.
Poor circulation of blood.
Route of admission
Injection.
Orally.
Topical.
Storage
Well closed container.
Cool, dry place.
Away from light
2-30 degrees.
prednisolone
Mechanism of action
Easy passage through cell membrane
Binds to glucocorticoid.
Supressed immune systems
Produce anti-inflammatory response.
Indications
Allergies.
Inflammatory conditions.
Autoimmune disorders.
Cancers.
Nursing considerations.
Side effects
Polyphagia.
Weight gain.
Nausea
Malaise.
Skin thinning.
Menstrual abnormalities.
Route of administration
Orally.
Contraindications
Peptic ulcers.
Osteoporosis.
Psychosis.
Infections.
Diabetes mellitus.
Hypertension.
Storage
Cool, dry place.
Triamcinolone
Mechanism of action
Interact with glucocortiod.
Alters gene expression
Inhibit arachidonic acid
Control biosynthesis
Prostaglandin
Indications
Treat inflammation.
Allergies.
Eczema.
Rash.
Nursing considerations
Side effects
Burning.
Dryness.
Itching.
Irritation.
Headache.
Contraindications
Diabetes mellitus.
Hypothyroidism.
Untreated tuberculosis.
Herpes simplex infection
Eye.
Intestinal infection
Storage
Room temperature
15-30 degrees.
Away from light.
Kept away from children and pet.
Route of administration
Injection.