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tofacinitib (contraindication (• Active turberculosis, • …
tofacinitib
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side effects
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• Cold symptoms such as sore throat, runny nose
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mechanism of action
Tofacinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis Cytokines work within complex regulatory network in RA, signalling through different intracellular kinase pathways to modulate recruitment, activation and function immune cells other leukocytes
route of administration
• Oral administration, usually 5mg twice a day