ophthalmic( Loteprednol)
indications
name
contraindications
mechanism of action
Loteprednol
side effects
storage condition
route of adminstraton
Tuberculosis of the eye
signs of new infection such as swelling, redness, irritation
The mechanism of action of loteprednol is as a corticosteroid hormone receptor agonist. It a topical corticoid anti-inflammatory. corticosteroid inhibit response to a variety of inciting agents and may delay slow healing. they inhibit the oedema, fibrin deposition, capillary dilation, leucocyte migration, capillary proliferation, fibroblast inflammation. there is no generally accepted explanation for mechanism of action of the ocular corticosteroid.. therefore corticosteroid are thought to act by the induction of phospholipase A2 inhibitory protein and it called lipocortins.
seeing halos around light
eye pain
blurred vision
severe pain, burning, when using eye drop
headache
watery eye
runny nose or sore throat
dry eye
it is administered topically to the eye
store upright
away from children
sore between 59 to 77 degree F
do not freeze
increased pressure
herpes simplex dendritic keratitis
fungal infection of the eye
cornea of eye infection from vaccinia virus
allergic to corticosteroid (glucocorticoids)
treat certain eye conditions due to inflammation or injury
used after eye surgry
work to relieving symptoms such as swelling, redness and itching