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Random Block 9 notes (HIV cycle + Pharmo (Reverse transcriptase RNA to…
Random Block 9 notes
HIV cycle + Pharmo
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HIV polyproteins - Cleaved by protease. (amprenavir, atazamanvir)
Encapsidation ssRNA, budding and release
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Vaccination
1 Year: Hib, men C, MMR, Men B
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5 in 1 - 8 week, 12, 16 weeks (Diptheria, hib, pertussis, polio, tetanus)
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3 yrs 4months: 4 in 1, MMR
School: Tetanus, diptheria, polio, Men ACWY
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Hypersensitivity
T2: Antibodies react with antigens on cell membrane: Cascade dependent. Lysis/blockage of receptor - Grave's, M gravis
T3: Immune complex embed in tissue. Arthus reaction: urticaria, glomerulonephritis
T1: Immediate reaction of IgE bound to Mast cell. Histamine, chemokines etc. Allergic reaction, anaphylaxis
T4: Cell mediated- T cells + antigen. DMT1, RA, dermatitis.