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EVEROLIMUS (side effects (hypertension, oedema, pericardial effusion,…
EVEROLIMUS
side effects
hypertension
oedema
pericardial effusion
leucopnenia, thrombocytopinea
pain
Mechanism of action
inhibits proliferation of activated T-cells
binds to T-cell growth factor receptor site
hence blocking G1 stage of cell cycle
contraindications
don't drink grape juice
may increase renal toxicity of cyclosporin
not to be taken with ketoconazole
indications
prevention of organ rejection
following a renal or heart transplant
route of administration
orally
storage conditions
room temperature