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CYCLOSPORINE (CONTRAINDICATION (Infection, cancer, high cholesterol,…
CYCLOSPORINE
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INDICATION
For treatment of transplant (kidney, liver and heart) rejection, rheumatoid arthritis, severe psoriasis
MECHANISM OF ACTION
The exact mechanism of action of cyclosporine is not known, experimental evidence suggest that the effectiveness of cyclosporine is due to specific and reversible inhibition of immunocompetent lymphocytes in the GO-OR G1-phase of the cell cycle.
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