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Antineoplastic Drugs (Azacitidine (Indication (Acute myeloid leukemia,…
Antineoplastic Drugs
Azacitidine
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Side effect
Diarrhoea, headache, anxiety, insomia
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Contraindications
It is contraindicated to patient with known hypersensitivity and also patients with advanced malignant hepatic tumors
Capecitabine
Side effect
Stomach pain, loss of appetite, constipation, Back or joint pain, tiredness, severe nausea or vomiting
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Indications
Breast cancer, Colorectal cancer, Oesophageal cancer, gastric cancer
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Carmofur
Mechanism of action
Highly potent acid ceramidase (AC) inhibitor. Inhibition of AC activity sensitize tumour cells to the effect of antineoplastic agents
Contraindications
Contraindicated to patients with bone marrow suppression, also contraindicated in pregnant or breast feeding women and should be avoided in patients with malignant illness
Indications
Colorectal cancer. Breast cancer, Ovarian cancer
Storage condition
Store at temperature between 2 to 8 degrees. Keep the container tightly closed and keep away from fire
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Side effect
Diarrhea,Nausea and possible occasional vomiting, Poor appetite, Mouth sores, Watery eyes or photophobia
Hydroxycarbamine
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Indications
Chronic myeloid leukaemia, Sickle cell anaemia, Acute myeloid anemia
Side effect
Dysuria, More chills, Hoarseness, Cough, Blact tarry stool)
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Contraindications
Contraindicated to patients allergic to hydrxycarbamide, Breast feeding women, i