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Stroke (Treatment (After Ischaemic (Anti HTs, Anti-coagulants,…

- - - - 17 CEAS to prevent 1 death
      - 65% relative risk reduction, 17% absolute for symptomatic
- - - - Don't benefit individual nor percieved
      - Benefit community (smoking, exercise, diet, BP
    - - Treating asymptomatic conds. SEs.
      - Converse to above
- - - - 20% stroke have DM
      - 40% DM have HT
      - Increase risk stroke 2-4x.
      - 76% stroke 35-44 IDDM
    - - High shear, rupture and aneurysm
      - Small vessel disease- lacunar stroke
      - Accelerated athersclerosis
      - 50% less risk/ 7.5mmHg drop
    - - 35% untreated AF -> stroke
      - 16% strokes assoc. AF
      - <1% under 65, over 10% 85+
      - x17 risk w/ rheumatic HD
      - Anti-coagulants: Decrease risk 70%, aspirin less so.
    - - Men >20/day= 3.3 infarct, 2.4 heam
      - Men <20/day= 2.9 infarct, 1.7 haem
      - 10% stroke assoc.
      - Women <20/day = 3.9 stroke
    - - DM
      - Prior TIA etc
      - HT
      - Vascular condition (MI, plaques)
      - CHD
      - Sex (female +1)
      - Age 75+
      - Age 65-74
    - - REduce cholsterol >5mmol/L prevents 70/1000
      - RCP: Treat chol if >3.5mmol/L
      - Statins only for 1ry prevention in presence of other RF
      - NICE: >4 cholesterol, >2 LDL = treat
- - - - Vaculitis
      - Cardioembolism, PFO
      - Dissection
      - Genetic: CADASIL
    - - Aneurysm
      - Severe HT, clotting disorders
      - Ateriovenous malformation