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drugs used to treat obesity (orilistat (mechanism of action (inhibits the…
drugs used to treat obesity
orilistat
mechanism of action
inhibits the action if lipase in the intestine ,thus reducing fat absorption .
produce fat absorption
reduce weight
to reduce appetite
contraindications
pregnant mothers
if a patient had an organ transplant
gallbladder
kidney disease
side effects
severe stomach crams
blood in the urine
liver problems
indications
reduce body eight
treat cholesterol
storage conditions
store at room temperature
store in a dry place away from water
keep on a safe place , out of the children and pets
route of administration
oral
rimonabant
mechanism of action
rimonabant is a specific CB1 cannabinoid receptor antagonist
plays a role in appetite drive
treat disorders that might have a component of excess appetitive drive such as obesity or drug abuse
treat nervous system disorders and other disorders
indications
to treat obese or overweight patients who suffer from diabetes type2
to treat obesity
reduce appetite
route of administration
oral
side effects
nausea
upper respiratory tract infections
anxiety
insomnia
storage conditions
store at room temperature
contraindications
patients diagnosed with depression or has symptoms of mental disorders
pregnant women
should not be given to patients with renal or hepatic failure
sibutramine
side effects
difficult in breathing
swelling in your face
swelling in the lips , tongue or throat
contraindications
if a patient has severe or uncontrolled hypertension
if a patient has history of coronary artery disease
a history of heart attack or stroke
if a patient has a eating disorder , anorexia or bulimia
storage conditions
should be stored in a tight , light -resistant container
route of administration
oral
mechanism of action
blocks noradrenalin and 5 HT serotonin reuptake into the nerve terminal
gives sensation of satiety (having eaten enough )
also inhibit noradrenalin and 5HT reuptake
indications
assist with weight loss
affects chemicals in the brain that affect weight maintenance
xenicals
mechanism of action
decrease food consumption
promote satiety by activating 5-HT2C receptors on anorexigenic pro opiomelanocortin neurons located in hypothalamus
indications
to treat high cholesterol
to treat obesity
to increase physical activity
rout of administration
orally
side effects
nausea
dry mouth
headach
dizziness
constipation
contraindications
patients diagnosed with hypertension
patients with cardiovascular desease
storage and conditions
keep away from light
store in a cool dry place