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The advantages of circular mating (Theodorou et al., 2010) (METHODS (LOCI…
The advantages of circular mating (Theodorou et al., 2010)
- In circular mating fitness does not vary with population size and in cases of random mating, fitness must be high during mating.
- Therefore, parental contributions are set to produce in minimum co ancestry in order circular mating to work.
METHODS
LOCI SUBJECT TO SELECTION
- Fitness was controlled by a large number of freely recombining biallelic loci. Also, loci act multiplicative on fitness.
- The initial population were formed by sampling randomly from an infinite population at mutation-selection balance.
MANAGEMENT PROCEDURE
- Individuals are assumed to be unrelated.
- The succession of events was mutation, reproduction and viability selection.
- Compared an unmanaged population with method of Gc/Mc and circular mating.
Gc/Mc METHOD
- Comprises 2 steps altogether. Choose individuals from stock pool to the population minimum mean pairwise coancestry.
CIRCULAR MATING
- The number of offspring and viability selection was simulated as for the Gc/Mc method.
RANDOM MATING
- It is an unmanged population where the couples are randomly mate with each other.
REINTRODUCTION TO THE WILD
- Stimulated after 20 generations in captivity. The released population can increase in size. The life cycle iterated for 100 generations and 1000 replicates.
NEUTRAL VARIATION
- Assumed 200 freely recombining neutral loci.
RESULTS (A+B)
Genetic Variability
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Circular mating suggest that in a single generation of outcrossing should suffice to restore both gene diversity and population fitness
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DISCUSSION
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However, these disadvantages can be solved when in captivity
Captivity usually implies relatively benign conditions (no predators, provisioning of food and medical care)
Simpler to implement - Gc/mc method require knowledge of the pedigree of all individuals in the population, which is not always achievable while circular mating can be applied without any prior knowledges on pairwise coancestries or molecular information
Genetic load is due to slightly deleterious partly recessive alleles with high mutations rates and to rare lethal alles
Conclusion
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Even if population sizes increase, they remain initially small for several generations
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Suggestion
Do experimental works dealing with the effects of serial inbreeding on genetic load should test the efficiency of circular mating
INTRODUCTION
Advantages of Circular Mating:
- Reduced mean pairwise co ancestry in all population size.
- Increased efficiency of purging deleterious alleles.
- Increased probability released based on Gc/Mc method.
Disadvantages of Circular Mating:
- Increased inbreeding rates.
- Reduced fitness in early generations.
- Increasing extinction probability in captivity due to low population size and small litter size.